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Proteases are the enzymes that perform proteolysis; protein catabolism by hydrolysis of peptide bonds. Proteases have evolved multiple times, and different classes of proteases can perform the same reaction by completely different catalytic mechanisms. Proteases can be found in Animalia, Plantae, Fungi, Bacteria, Archaea and viruses. Creative Enzymes is honor to supply a broad range of proteases with multiple functions for various applications in both industrial and research use.

Proteases for Industrial Use Selection Guide

Categories Cat. No. Product Name  
Food & Beverage BAK-1723 Protease for baking Get a quote
BAK-1730 Neutral Protease for pet food Get a quote
BER-001 Neutral Protease for Beer Brewing (Food Grade) Get a quote
Agriculture & Bioenergy ASE-3112 Protease enzyme for fermentation Get a quote
Detergent DETE-2625 Neutral bacterial protease for detergent Get a quote
DETE-2633 Non-bacterial protease for Medical Get a quote
Cosmetic BODY-2813 Proteases enzyme blend for creams Get a quote
BODY-2814 Proteases enzyme blend for skin cleansers Get a quote
BODY-2816 Natural protease-enzyme blend for hair care Get a quote
BODY-2818 Protease-based enzyme formulation for toothpaste Get a quote

Proteases with Different Recognition Sites Selection Guide

Creative Enzymes offers products with different substrate specificity. For example, NATE-0220 is a serine endoproteinase that cleaves peptide bonds at the carboxyl side of lysine. NATE-1274 and NATE-0730 selectively cleave peptide bonds N-terminal to aspartic acid residues and C-terminal to glutamic acid, respectively. These proteases are ideal for proteome analysis by mass spectrophotometry. Proteinase K (NATE-0221) is a non-specific, subtilisin-related serine protease with a very high specific activity. Furin (NATE-0268) is a ubiquitous subtilisin-like proprotein convertase with a minimal cleavage site requirement of Arg-Xaa-(Lys/Arg)-Arg.

Categories Cat. No. Product Name  
Aspartic proteases NATE-1274 Native Flavobacterium menigosepticum Endoproteinase AspN Get a quote
NATE-0222 Native Pseudomonas fragi mutant strain Endoproteinase Asp-N Get a quote
Glutamic proteases NATE-1763 Immobilized Endoproteinase Glu-C on F7m Get a quote
NATE-1764 Immobilized Endoproteinase Glu-C on G3m Get a quote
NATE-0730 Native Staph aureus V8 Protease (Endoproteinase Glu-C) Get a quote
Serine proteases NATE-0221 Native Tritirachium album Proteinase K Get a quote
NATE-1768 Immobilized Proteinase K on G3m Get a quote
Others NATE-0220 Native Lysobacter enzymogenes Endoproteinase Lys-C Get a quote
NATE-0268 Furin from Human, Recombinant Get a quote
Except for these enzymes, Creative Enzymes also provides various proteases with multiple functions and substrate specificity. To get more information of these products, please call 1-631-562-8517 or e-mail us at:, or use our contact page: Contact.

Examples of different properties of various protease products.

Cat. No. Name Optimum Temperature (°C) Active Temperature Range
NATE-0633 Native Bacillus licheniformis Protease 55-60
NATE-1240 Proteinase K from Tritirachium album limber, Recombinant 58 25-65 °C
NATE-1594 Collagenase 50-55
BER-001 Neutral Protease 45-55
NATE-0997 Native Streptomyces griseus Pronase 35-40
NATE-0548 Native Porcine Peptidase 37
NATE-0628 Native Bovine Protease 37
NATE-0629 Native Rhizopus sp. Protease 37
NATE-0631 Native Aspergillus oryzae Protease 37
NATE-0221 Native Tritirachium album Proteinase K 37 20-60 °C
NATE-0637 Native Tritirachium album limber Proteinase K 37 20-60 °C
NATE-0922 Tobacco Etch Virus Protease, Recombinant 30
NATE-0817 Chymase from Human, Recombinant 25

* More products are available for your specific need. Please contact us for technical details.

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